Protein Purification
Selleck Chemical LLC Baicalin 10mg 21967-41-9
Baicalin is a known prolyl endopeptidase inhibitor and affects the GABA receptors. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC TG100-115 50mg 677297-51-7
TG100-115 is a PI3K?/? inhibitor with IC50 of 83 nM/235 nM, with little effect on PI3K?/?. Phase 1/2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Selleck Chemical LLC AS-605240 5mg 648450-29-7
AS-605240 selectively inhibits PI3K? with IC50 of 8 nM, over 30-fold and 7.5-fold more selective for PI3K? than PI3K?/? and PI3K? in cell-free assays, respectively. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Brm/brg1 atp inhibitor-2 | 2368900-77-8 | 99.7% | C20H20N4O2S2 | 50 MG
BRM/BRG1 ATP Inhibitor-2 is an ATPase inhibitor for the research of BAF-related disorders. It has a molecular weight of 412.53 and appears as a white to off-white solid. It is soluble in DMSO at 100 mg/mL. Stock solutions can be stored at -80°C for 6 months or -20°C for 1 month.
- For research use only
- White to off-white solid appearance
- Soluble in DMSO
- Powder stable for 3 years at -20°C
- Solutions stable for 6 months at -80°C
Echelon Biosciences Research Labs BODIPY TMR-PTDINS(4)P 100 ug
BODIPY TMR PI(4)P (BODIPY TMR Phosphatidylinositol 4-phosphate) is a water soluble analog of PI(4)P labeled with the orange fluorophore, Bodipy-TMR, at the sn-1 position.Phosphoinositides (PIPns) are minor components of cellular membranes but are integral signaling molecules for cellular communication. Phosphatidylinositol 4-phosphate (PI(4)P) is the biosynthetic precursor to PI(4,5)P2 and has an important roles in regulating sphingomyelin and glycosphingolipid metabolism and membrane trafficking at the exit of the Golgi complex. This item is non returnable
Selleck Chemical LLC AT7867 50mg 857531-00-1
AT7867 is a potent ATP-competitive inhibitor of Akt1/2/3 and p70S6K/PKA with IC50 of 32 nM/17 nM/47 nM and 85 nM/20 nM in cell-free assays, respectively; little activity outside the AGC kinase family. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Cayman Chemical NFKB ActIvatIon InHBTr II 25mg
An inhibitor of NF-κB activation; inhibits TNF-α-induced NF-κB activation in HT-1080 cells at 20 µM; inhibits TNF-α-induced expression of MMP-9 in HT-1080 cells; decreases TNF-α-induced migration of HT-1080 cells at 20 µM; inhibits IL-6 release induced by TNF-α from primary rat brain pericytes at 1, 5, and 10 µM; increases IL-8 secretion in HT-29 and Caco-2 cells at 5 µM in combination with glyoxal
Electron Microscopy Sciences Substrate of Silver Coated Microscope Slide, 25 x 75 mm
EMS offers a variety of economically priced coated substrates. All coatings are deposited under vacuum using electron beam evaporation. These high quality substrates are coated with 500 Angstroms (50 nm) of silver, with a thin titanium adhesion layer (2-7 nm) between the glass and silver coating. All substrates are pre-cleaned using an ion source for quality assurance. Autoclavable. Packed in a cleanroom. Shipped in slide mailers.
Dimensions: 25 x 75 mm
Material: Soda lime glass
Abcam Serine Protease Assay Kit (FAM-Spacer-Leu-CMK), 100 Tests
These Serine Protease Assay Kits enable researchers to detect intracellular chymotrypsin-like serine protease activity in vitro without lysing the cell.
The product is subject to the following: Abcam Restricted Use Statement
Abcam Enalaprilat, Angiotensin II converting enzyme inhibitor, 250MG
MW 384.4 Da, Purity >99%. Angiotensin II converting enzyme inhibitor. Inhibits angiotensin II-induced cardiac fibroblast proliferation. Active metabolite of Enalapril (ab141929). Antihypertensive agent. Active in vivo and in vitro.
The product is subject to the following: Abcam Restricted Use Statement
Selleck Chemical LLC Pictilisib (GDC-0941) 200mg 957054-30-7 RG7321
Pictilisib (GDC-0941, RG7321) is a potent inhibitor of PI3K?/? with IC50 of 3 nM in cell-free assays, with modest selectivity against p110? (11-fold) and p110? (25-fold). Pictilisib (GDC-0941) induces autophagy and apoptosis. Phase 2. *For Research & Development use only. Product is not intended for drug, household, or human consumption.
Medchemexpress LLC Trequinsin hydrochloride | 78416-81-6 | 99.9% | 441.95 | C24H28ClN3O3 | 10 MG
Trequinsin hydrochloride is a research-grade phosphodiesterase (PDE) inhibitor supplied as the hydrochloride salt in solid form. It potently inhibits platelet cAMP PDE and reduces platelet aggregation in vitro, making it suitable for biochemical and cellular assays requiring a highly potent PDE modulator.
- High purity (99.9%).
- Potent PDE inhibition (IC50 ≈ 0.25 nM).
- Soluble in DMSO and water; may require ultrasonic assistance.
- Stable when stored sealed at 4°C; in solution store at -80°C for long-term.
- Supplied in small solid aliquots suitable for assay preparation.
Medchemexpress LLC Calcineurin autoinhibitory peptide | 148067-21-4 | 100.0% | 2930.32 | 10 MG
Calcineurin autoinhibitory peptide is a selective inhibitor of Ca2+/calmodulin-dependent protein phosphatase (calcineurin). It could protect neurons from excitatory neuronal death.
- Selective inhibitor of calcineurin
- IC50 of approximately 10 μM
- Protects neurons from excitatory neuronal death
Enzo Life Sciences Microcystin-LA (25µg). CAS: 96180-79-9
Analog of microcystin-LR (ALX-350-012) with Ala substituted in place of Arg. Inhibits protein phosphatase 2A (PP2A) and protein phosphatase 3 (PP3) more potently than protein phosphatase 1 (PP1). Ozonation of toxic water samples does lead to a complete loss of the microcystins and their toxicity. Purity: ≥95% (HPLC). Appearance: Whitish film adhered to inside of the vial. Solubility: Soluble in 100% ethanol or methanol. Long Term Storage: -20°C.